{ "_id": "6a103823acfb0bcc41c9a9b1", "Package": "powerpkg", "Type": "Package", "Title": "Power Analyses for the Affected Sib Pair and the TDT Design", "Version": "1.6", "Date": "2022-05-18", "Author": "Daniel E. Weeks", "Maintainer": "Daniel E. Weeks ", "Description": "There are two main functions: (1) To estimate the power of\ntesting for linkage using an affected sib pair design, as a\nfunction of the recurrence risk ratios. We will use analytical\npower formulae as implemented in R. These are based on a\nMathematica notebook created by Martin Farrall. (2) To examine\nhow the power of the transmission disequilibrium test (TDT)\ndepends on the disease allele frequency, the marker allele\nfrequency, the strength of the linkage disequilibrium, and the\nmagnitude of the genetic effect. We will use an R program that\nimplements the power formulae of Abel and Muller-Myhsok (1998).\nThese formulae allow one to quickly compute power of the TDT\napproach under a variety of different conditions. This R\nprogram was modeled on Martin Farrall's Mathematica notebook.", "License": "GPL (>= 2)", "Packaged": { "Date": "2026-05-12 06:03:59 UTC", "User": "root" }, "NeedsCompilation": "no", "Repository": "https://danieleweeks.r-universe.dev", "Date/Publication": "2022-05-19 05:50:02 UTC", "RemoteUrl": "https://github.com/cran/powerpkg", "RemoteRef": "HEAD", "RemoteSha": "006fe9bf0fa70d738eb28b49c7161c27e2704cff", "MD5sum": "061f0c3fca0f0672f17f445e77c351cb", "_user": "danieleweeks", "_type": "src", "_file": "powerpkg_1.6.tar.gz", "_fileid": "bcf7dbbdb05816232be7313e5f7860329d90de137dc43f2952cd33ce25abf2f2", "_filesize": 125496, "_sha256": "bcf7dbbdb05816232be7313e5f7860329d90de137dc43f2952cd33ce25abf2f2", "_created": "2026-05-12T06:03:59.000Z", "_published": "2026-05-22T11:04:03.580Z", "_distro": "noble", "_jobs": [ { "job": 77366967285, "time": 96, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "6936855800" }, { "job": 77366967729, "time": 99, "config": "linux-release-x86_64", "r": "4.6.0", "check": "OK", "artifact": "6936857842" }, { "job": 77366967521, "time": 182, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "OK", "artifact": "6936866902" }, { "job": 77366967220, "time": 248, "config": "macos-release-arm64", "r": "4.6.0", "check": "OK", "artifact": "6936886604" }, { "job": 77366967056, "time": 188, "config": "source", "r": "4.6.0", "check": "OK", "artifact": "6936833196" }, { "job": 77366966880, "time": 91, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "7158958878" }, { "job": 77366967321, "time": 101, "config": "windows-devel", "r": "4.7.0", "check": "OK", "artifact": "6936856855" }, { "job": 77366967518, "time": 88, "config": "windows-oldrel", "r": "4.5.3", "check": "OK", "artifact": "6936854137" }, { "job": 77366967641, "time": 69, "config": "windows-release", "r": "4.6.0", "check": "OK", "artifact": "6936849178" } ], "_buildurl": "https://github.com/r-universe/danieleweeks/actions/runs/25716460590", "_status": "success", "_host": "GitHub-Actions", "_upstream": "https://github.com/cran/powerpkg", "_commit": { "id": "006fe9bf0fa70d738eb28b49c7161c27e2704cff", "author": "Daniel E. Weeks ", "committer": "cran-robot ", "message": "version 1.6\n", "time": 1652939402 }, "_maintainer": { "name": "Daniel E. Weeks", "email": "weeks@pitt.edu", "login": "danieleweeks", "mastodon": "@StatGenDan@fediscience.org", "orcid": "0000-0001-9410-7228", "twitter": "@StatGenDan", "uuid": 8495972 }, "_registered": true, "_dependencies": [ { "package": "tcltk", "role": "Depends" } ], "_owner": "cran", "_selfowned": true, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 0, "_contributors": [ { "user": "danieleweeks", "count": 3, "uuid": 8495972 }, { "user": "daniel-e-weeks", "count": 2, "uuid": 54481044 } ], "_userbio": { "uuid": 8495972, "type": "user", "name": "Daniel E. Weeks" }, "_downloads": { "count": 187, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/powerpkg" }, "_mentions": 1, "_searchresults": 10, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/powerpkg.html", "manual.pdf" ], "_realowner": "danieleweeks", "_cranurl": false, "_releases": [ { "version": "1.2", "date": "2006-02-08" }, { "version": "1.3", "date": "2010-09-11" }, { "version": "1.4", "date": "2012-03-27" }, { "version": "1.5", "date": "2012-10-11" }, { "version": "1.6", "date": "2022-05-19" } ], "_exports": [ "fnfam", "fx", "normplot", "nsibs", "ntdt", "ntdt.q", "plotDom", "plotNsibs", "plotNtdt", "ptb", "ptdt" ], "_help": [ { "page": "normplot", "title": "Power plotting demonstration", "topics": [ "normplot" ] }, { "page": "nsibs", "title": "A function to compute power of an affected sib pair design.", "topics": [ "nsibs" ] }, { "page": "ntdt", "title": "Computes number of trios needed for a TDT study.", "topics": [ "ntdt" ] }, { "page": "ntdt.q", "title": "Computes power of a TDT study as a function of the susceptibility allele frequency q.", "topics": [ "ntdt.q" ] }, { "page": "plotDom", "title": "plotDom creates power graphs for an affected sibpair linkage study.", "topics": [ "plotDom" ] }, { "page": "plotNsibs", "title": "plotNsibs: Create power plots for an affected sib pair linkage study", "topics": [ "plotNsibs" ] }, { "page": "plotNtdt", "title": "A function for plotting the results from ntdt.q", "topics": [ "plotNtdt" ] }, { "page": "ptb", "title": "A power table for the TDT design", "topics": [ "ptb" ] }, { "page": "ptdt", "title": "Power for a TDT design", "topics": [ "ptdt" ] } ], "_rundeps": [], "_score": 1, "_indexed": true, "_nocasepkg": "powerpkg", "_universes": [ "danieleweeks" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "1.6", "date": "2026-05-12T06:05:42.000Z", "distro": "noble", "commit": "006fe9bf0fa70d738eb28b49c7161c27e2704cff", "fileid": "5233cbbd97fc797eaf7b7e17192837aa3215f7cab8db95043536b763ccc126c6", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/danieleweeks/actions/runs/25716460590" }, { "r": "4.6.0", "os": "linux", "version": "1.6", "date": "2026-05-12T06:05:50.000Z", "distro": "noble", "commit": "006fe9bf0fa70d738eb28b49c7161c27e2704cff", "fileid": "42334ba02234bc8210493cd28751b3df272add1d65aeb08ed157cc3ba33ecaeb", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/danieleweeks/actions/runs/25716460590" }, { "r": "4.5.3", "os": "mac", "version": "1.6", "date": "2026-05-12T06:06:29.000Z", "commit": "006fe9bf0fa70d738eb28b49c7161c27e2704cff", "fileid": "f2bfafc4600a1eb96e4486763b1d7a0c24336861b5a5b5c3a29f82a6f2ab05d3", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/danieleweeks/actions/runs/25716460590" }, { "r": "4.6.0", "os": "mac", "version": "1.6", "date": "2026-05-12T06:07:52.000Z", "commit": "006fe9bf0fa70d738eb28b49c7161c27e2704cff", "fileid": "8bf93733ba1889bbdc5a3444a6d279333da5796aec8b130ded39d90d4aaa4798", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/danieleweeks/actions/runs/25716460590" }, { "r": "4.7.0", "os": "win", "version": "1.6", "date": "2026-05-12T06:05:42.000Z", "commit": "006fe9bf0fa70d738eb28b49c7161c27e2704cff", "fileid": "f52515b8031a51160b52bab21cb1292e9733f08633da2d1d834209d3c8db66c1", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/danieleweeks/actions/runs/25716460590" }, { "r": "4.5.3", "os": "win", "version": "1.6", "date": "2026-05-12T06:05:33.000Z", "commit": "006fe9bf0fa70d738eb28b49c7161c27e2704cff", "fileid": "7b1bb90dc7d1255c0ee27ddbe2ecdd2042e82b02ee914fb0bf91095c96a2d946", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/danieleweeks/actions/runs/25716460590" }, { "r": "4.6.0", "os": "win", "version": "1.6", "date": "2026-05-12T06:05:06.000Z", "commit": "006fe9bf0fa70d738eb28b49c7161c27e2704cff", "fileid": "6f7cb1cafcfa45c450d684b73462a6b69dda13208ab6f9cc306279e97459b6d3", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/danieleweeks/actions/runs/25716460590" }, { "r": "4.6.0", "os": "wasm", "version": "1.6", "date": "2026-05-22T11:03:48.000Z", "commit": "006fe9bf0fa70d738eb28b49c7161c27e2704cff", "fileid": "23f2fa4366c27ebc38af3b3bb5b196c3a6dcfb8b7bd98d4601210c8edfc1c8f2", "status": "success", "buildurl": "https://github.com/r-universe/danieleweeks/actions/runs/25716460590" } ] }